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Molecular sieves are materials with pores of uniform size and diameter that are similar in size to small molecules; used to separate molecules by size; available in various pore size ranges, with drying solvent indicators, etc.
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AVG-233 is a potent, orally active RNA-dependent RNA polymerase (RdRp) inhibitor used for research into respiratory syncytial virus (RSV). It prevents initiation of the viral polymerase complex and shows nanomolar activity against RSV strains and clinical isolates.
Potent RNA-dependent RNA polymerase inhibitor.
Reported EC50 = 0.14-0.31 μM against RSV strains and clinical isolates.
Molecular formula: C26H22ClN5O3.
Molecular weight: 487.94 g/mol.
Available as a solid in multiple pack sizes (5 mg-500 mg).
Intended for research use only; not for human or diagnostic use.
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Nutlin-3a is a small-molecule MDM2 antagonist used in research to activate wild-type p53, stabilize p53 protein, and induce apoptosis and autophagy. It is intended for laboratory research use and is characterized for cell-based and biochemical assays.
Inhibits MDM2-p53 interaction, leading to p53 activation.
Induces apoptosis and autophagy in p53 wild-type cells.
High reported purity (≈99.1%) suitable for research applications.
Molecular formula C30H30Cl2N4O4 and molecular weight ~581.5 g/mol.
Available in multiple solid and solution sizes for experimental flexibility.
For research use only; not for human or animal therapeutic use.
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TCS-PIM-1-4a is a small-molecule inhibitor targeting Pim kinases a family of serine/threonine kinases It is designed to selectively inhibit Pim kinases thereby modulating signaling pathways related to cell growth and survival TCS-PIM-1-4a exerts its biological activity primarily through activation of AMP-activated protein kinase (AMPK) resulting in inhibition of the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway In cell-based studies TCS-PIM-1-4a demonstrates cytotoxic activity against diverse hematological tumor cell lines including myeloid and lymphoid subtypes with IC50 values ranging from approximately 0 8 to 40 M Based on these pharmacological properties TCS-PIM-1-4a holds research potential in investigations of Pim kinase signaling and therapeutic strategies for hematological malignancies
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3α-Angeloyloxypterokaurene L3 is a Diterpenoids product isolated from the herbs of *Wedelia trilobata*. It is a white to off-white solid, primarily classified under Terpenoids and Diterpenoids, with initial sources from plants such as Leguminosae (*Senna siamea*) and Compositae. This compound is intended for research purposes only.
Isolated from *Wedelia trilobata* and other plant sources.
Diterpenoid product.
Appears as a white to off-white solid.
High purity (98.0%).
Specific storage conditions (-20°C, sealed, away from moisture and light) ensure product stability.
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Regeneration or ActivationA saturated molecular sieve can be restored to its original capacity by regeneration the principle of which involves changing the conditions surrounding the adsorbent to correspond to a very low equilibrium capacity. In general the greater the difference between the equilibrium capacities of adsorption and regeneration the more rapid and complete the regeneration.The sieve may be regenerated in one of four ways1. Thermal reactivation -The maximum regeneration temperature for Silica is 300C.2. Pressure reactivation3. Passing an appropriate fluid through the gel bed at normal temperature and pressure.4. Displacement of adsorbates by passing a high concentration of molecules in a fluid through the bed.
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